Fundamentals of Physiopathology - LEB


Biomedical Engineering

Curricular Unit (UC)

Fundamentals of Physiopathology

Mandatory  x
Scientific Area BS Category  

Course category: B - Basic; C - Core Engineering; E - Specialization; P - Complementary.

Year: 3rd Semester: 1st ECTS: 5 Total Hours: 135
Contact Hours T: 45 TP: 22.5 PL: S: OT:2
Professor in charge

 Virgínia Maria dos Prazeres Fonseca

T - Lectures; TP - Theory and practice; PL - Lab Work; S - Seminar; OT - Tutorial Guidance.

  • Learning outcomes of the curricular unit


    At the end of the course the student should be able to:


    Identify the concept of health/ disease and the implications in the lifecycle of the human being.


    Learning about the mechanism of morphological and functional changes in the system during the course of a disease.


    Identify the main etiological factors of functional and organ changes.

    Recognize the general auxiliary means for basic diagnosis, applied in the study of the main organs and systems.

  • Syllabus

    Healthcare terminology.

    Introduction: natural history of diseases. Concept of health/ disease. Etiology – pathogenesis – evolution. Semilogical study. Diagnostic process/ definition of problem. Treatment plan/ decision making. General considerations of complementary diagnosis means. Disease classification models.

    Principles of epidemiology.

    Basic pathophisyology  models: cell damage, immunity inflammation, body heat regulation (fever), pain, bofy fluid regulation (edema).

    Pathophisyology of cardiovascular diseases.

    Pathophisyology of diseases of respiratory system.

    Pathophisyology of diseases of the digestive system.

    Pathophisyology of diseases of the urinary system.

    Pathophisyology of blood diseases

    Pathophisyology of endocrinic diseases.

  • Demonstration of the syllabus coherence with the curricular unit's objectives

    The course covers basic concepts related to the abnormal function and change in various organs systems in the face of diseases. Effects of diseases and other pathological agents are of primary concern, rather than the biology of the agents themselves. Common diseases and disorders are covered and emphasis is given to cardiovascular, respiratory, digestive, urinary, blood and endocrine systems. The illustrations reinforces theoretical concepts through the use of software and images.

    The approach of contents will be adjusted to the goals of the academic course in Biomedical Engineering.

  • Teaching methodologies (including evaluation):

    Teaching methodologies:

    Lectures by the teacher of the type demonstration and explanation. Work group on the themes developed.

    The continuous theoretical assessment includes one written test (70%) and a work group (30%).

    Written exam (100%) – 1 written test.

    The minimum rating for the student to be considered approved is 10 values.

  • Demonstration of the coherence between the teaching methodologies and the learning outcomes.

    The use of expository lectures and active classes in the learning process allows the exemplification of the application of theoretical concepts transmitted to students. During classes students are stimulated to participate in the problem solving.


  • Main Bibliography:

    A. Stevens, J. Low. Patologia. Ed. Manole Ltd, Brasil.

    Bonita, Beaglehole, Kjellstrom. Basic Epidemiology. 2nd. Ed., World Health Organization, 2006.

    E.P.Widmaier, H. Raff, K. T. Strang. Vanders Human Physiology: The mechanism of the body function. 11th ed., McGraw Hill, 2008.

    G.D. Hammer. Pathophysiology of diseases: an introduction to clinical medicine. 7th. Ed., McGrawHill, 2008.

    A.M. Pinto. Fisiologia: fundamentos e aplicações. 2ª ed., Lidel, 2009.

    C.L. Vanputte, P. Tate, T.D. Stephensen, R.R. Seeley, Seeleys Anatomy & physiology. McGraw Hill. 10th. Ed., 2013.